General Cell Based Assays
ABclonal Technology ADAM17 Rabbit pAb
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) family, which includes membrane-anchored proteins related to snake venom disintegrins. These proteins are involved in various biological processes such as fertilization, muscle development, and neurogenesis. The preproprotein is processed to produce the mature protease, which sheds the ectodomain of tumor necrosis factor-alpha (TNF-alpha), releasing soluble TNF-alpha. This protease also processes cell adhesion proteins, cytokine and growth factor receptors, and EGF receptor ligands, and activates the Notch signaling pathway. Elevated expression of this gene has been linked to psoriasis, rheumatoid arthritis, multiple sclerosis, and Crohn’s disease, suggesting a role in autoimmune diseases. Additionally, the protease may play a role in viral infection by cleaving ACE2, the receptor for SARS-CoV and SARS-CoV-2.
Revvity Health Sciences Inc HTRF mAb Anti-FLAG XL665-Conjugate, 5,000 Assay Points
HTRF mAb Anti-FLAG XL665-Conjugate, 5,000 Assay Points
Revvity Health Sciences Inc HTRF KinEASE detection buffer, 200 ml
HTRF KinEASE detection buffer, 200 ml
Enzo Life Sciences CHEMILUM DE LYS HDAC/SIRT Chemiluminescent drug discovery kit (1x96wells)
The HDAC/SIRT Chemiluminescent Drug Discovery Kit is a complete assay system designed to measure histone deacetylase and sirtuin activity in cell or nuclear extracts, immunoprecipitates or purified enzymes. The HDAC Chemiluminescent Activity Assay is based on the unique CHEMILUM DE LYS Substrate and Developer combination. The CHEMILUM DE LYS system is a highly sensitive and convenient alternative to radiolabeled, acetylated histones or peptide/HPLC methods for the assay of histone deacetylases. The assay procedure has three steps. First, the CHEMILUM DE LYS Substrate, which comprises an acetylated lysine side chain, is incubated with a sample containing HDAC activity . Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the CHEMILUM DE LYS Developer followed by Enhancer produces light. The reaction is luciferase-free Alternative name: Histone deacetylase fluorescent assay kit. Applications: Chemiluminescence, HTS Activity assay.
Eurofins Discoverx PathHunter Human P2RY1 β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human P2RY1 β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure P2RY1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human TrkC Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human TrkC Stable Cell Line Functional Kinase Assay (U2OS) measures TrkC receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CNR2 (CB2) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CNR2 (CB2) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CNR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical 3-Acetylpyridine NAD, Purity: ≥95%, CAS: 86-08-8, 250 mg
A NAD analog; used to study the mechanisms of oxidative phosphorylation
Eurofins Discoverx cAMP Hunter eXpress HRH3 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0103E2CP2M)
The cAMP Hunter HRH3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HRH3, a naturally Gi/Go coupled GPCR. Upon activation of HRH3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Enzo Life Sciences Express DNA methylation kit (50tests)
The Express DNA methylation kit can be used for rapid and reliable bisulfite treatment and conversion of DNA for methylation analysis. Simply add the Express Conversion Reagent for the reaction to occur. With the addition of heat, DNA denaturation is facilitated. Desulphonation and clean-up of the converted DNA is performed using a unique low-elution spin column. High yield, converted DNA is ideal for PCR, array, bisulfite and next generation sequencing, etc.
Eurofins Discoverx cAMP Hunter™ Human CXCL16 (CXCR6) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human CXCL16 (CXCR6) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CXCR6 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam TET Hydroxylase Activity Quantification Kit (Fluorometric)
TET Hydroxylase Activity Quantification Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Echelon Biosciences Research Labs PI(3,4,5)P3 DiC16 1 mg
PI(3,4,5)P3 diC16 (Phosphatidylinositol 3,4,5-trisphosphate diC16) is a synthetic, purified dipalmitoyl PI(3,4,5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This item is non returnable
TRIBIOSCIENCE INC Fast Glucose Oxidase Activity Assay (Colorimetric/Fluorometric) 200 Assays
Tribioscience’s Fast Glucose Oxidase Activity Assay uses a single working reagent that combines the glucose oxidase reaction and color reaction in one step. The change in color intensity of the reaction product at 570nm or fluorescence intensity at λ ex/em = 530/585 nm is directly proportional to glucose oxidase activity in the sample. The fluorometric assay is more sensitive than the colorimetric assay. Applications - Direct Assay - Glucose oxidase activity in serum, plasma, urine, and other bio-samples. Key Features - Flexible - Suitable for colorimetric and fluorometric methods. Accurate - Use 50μL samples. Detection ranges 0.1-50 μM in 96-well plate for colorimetric assay and 0.002-10 μM for fluorometric assay. Simple and High-Throughput - One-step procedure. Load-Incubate-Read. The kit can be used for a robust method. Time Saving - takes less than 30 minutes.
THORLABS INC Red First Contact™ Polymer Regular Cleaning Kit, For Optics
This cleaning kit utilizes a red polymer solution that is applied to optical surfaces. The solution conforms to the surface, dissolving organic material and trapping particles. Upon drying, it forms a film that can be peeled off, leaving a spotless, residue-free surface. This method is ideal for sensitive optics like diffraction gratings and AR-coated optics, ensuring thorough cleaning without damage.
- Polymer-based cleaning formula for safe, residue-free optic cleaning.
- Suitable for cleaning sensitive optics without damaging their structure and performance.
- Dried polymer film peels off, removing trapped particles.
- Leaves behind a contaminant-free optic with no residue.
- Ideal for cleaning diffraction gratings and AR-coated optics.